AIC Technica actively consults within the biotechnology industry. Our focus includes medical devices, biosensors, and the biopharmaceutical industry. Whether investigating the corrosion properties of an implantable device, the materials for a glucose sensor, or the synthesis of a pharmaceutical intermediate, our consultants have the industrial experience to guarantee your success.

Biotechnology

••••Biopharmaceuticals – Ion Channel Disease Sensing, Electrochemical Synthesis, Continuous Flow
•••• Microreactor Synthesis

• ••Medical Devices – Testing of Implantable Medical Devices in Accordance with FDA ASTM F2129

• ••Biosensors – Glucose Sensing, Metabolite Sensing

Biosensor Industry

Our sensor scientists are involved in a number of sensor projects including continuous and intermittent glucose/metabolite monitoring. Our scientist have skills ranging from redox mediator synthesis for biosensors to whole sensor design.

Our medical devices group can specifically advise on implantable devices, and FDA corrosion compliance. We develop, troubleshoot, and product improve biosensors and their instrumentation from hand-held to full bench top systems.

Our consultants are able to take sensor partners from concept to market:

• Evaluation of sensing protocol from photonics, voltammetry, • chronoamperometry, chronocoulometry to impedance • spectroscopy • Sensor formulation from self-assembled monolayers (SAMS) to • printed bioactive inks • Signal algorithms for maximum metabolite sensitivity, selectivity, • and rapid detection • Sensor electronics design and manufacture • Mechanical design, fabrication, and manufacturing

Biopharmaceutical Industry

We support the biopharmaceutical industry in ion channel/drug interaction and molecular synthesis.

Ion Channel Analysis

Our clients are biopharmaceutical companies whose portfolios include ion channel diseases.

AIC Technica’s strength in electroanalytic techniques gives our biopharmaceutical customers a unique perspective on the interaction of ion channels and drug molecules.

As well as traditional techniques of ion channel analysis, e.g. whole cell voltage clamping, capacitance clamping, and patch clamping, AIC Technica uses electrochemistry spectroscopy to probe deeper into the subtleties of drug/ion channel interactions.

Our biopharmaceutical partners achieve a structure activity relationship (SAR) knowledge of their drug/ion channel interactions through our studies, improving their drug discovery process.

Molecular Synthesis

Drug discovery

AIC Technica’s electrochemical expertise allows access to molecules not attainable by traditional synthetic techniques. Our biopharmaceutical customers are accessing unique scaffolds and thus avoiding patent infringements. Additionally, these clients achieve first-in-class drug success.

Process scale-up

AIC Technica consults on electrochemical synthesis for such processes as oxidations, reduction, and coupling reactions. Electrochemical synthesis is a unique process technology that does not require reagents, catalysts,
or extreme conditions. With AIC Technica, our biopharmaceutical partners achieve cost effective, reagentless,
and ambient condition processes. Our team of consultants can optimize electrochemical processes from bench
scale to GMP.

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